Dr Pallavi M Latthe

Consultant in Obstetrics & Gynaecology, Subspecialist in Urogynaecology



Phone: 0121 627 2672

Email: pallavi.latthe@bwhct.nhs.uk

My main research interests are systematic reviews and randomised controlled trials.

• Until recently, I was actively involved in recruiting patients in various ongoing medical and surgical multicentre studies from our department such as the RELAX (Botox versus placebo in idiopathic detrusor overactivity), CARPET(colposuspension versus anterior vaginal repair with TVT in stress incontinence withcystocele) and the Bulkamid bladder neck injection study.

• As WellBeing Research Fellow, I coordinated a multicentre double blind randomised trial on laparoscopic uterosacral nerve ablation in chronic pelvic pain which is now completed (September 2002-2004). In addition, I gained experience in conducting systematic reviews of prevalence, aetiology and effectiveness. I have been awarded MD on “Chronic pelvic pain: prevalence, aetiology and LUNA” by Birmingham University (July 2006).

• "A comparative study of intracervical PGE2 gel with intravenous oxytocin in the induction of labour"- I conducted this prospective randomised trial during my postgraduate training in India (1994-1997) and wrote it up as a dissertation for MD and MRCOG.

• I am now actively involved in supervising trainees with their research projects from conception of idea to providing guidance on methodology, statistics and writing up a manuscript.

PUBLICATIONS:

1. Jane Daniels; Richard Gray; Robert K. Hills; Pallavi Latthe; Laura Buckley; Janesh Gupta; Tara Selman; Elizabeth Adey; Tengbin Xiong; Rita Champaneria; Richard Lilford; Khalid S. Khan; on behalf of the LUNA Trial Collaboration. Laparoscopic Uterosacral Nerve Ablation for Alleviating Chronic Pelvic Pain: A Randomized Controlled Trial JAMA. 2009;302:955- 961; September 2, 2009:(doi:10.1001/jama.2009.1268).

2. Latthe P Review: some evidence shows that pelvic floor muscle training reduces urinary incontinence in pregnant and postpartum women at </=12 months. Evid Based Med. 2009 Apr; 14 (2):53.

3. Latthe PM, Toozs-Hobson P, Gray J. Mycoplasma / Ureaplasma colonisation in women with lower urinary tract symptoms. 2008 July; 28 (5): 1-3.

4. Latthe PM. Review of retropubic and transobturator tapes in stress urinary incontinence. Current Opinion in Obstet Gynecol, 2008, 20: 331-336.

5. Foon R, Toozs-Hobson P, Latthe PM. Adjuvant materials in anterior vaginal wall prolapse surgery: a systematic review of effectiveness and complications. Int Urogynecol J Pelvic Floor Dysfunct. 2008 Jul 8. [Epub ahead of print]

6. Latthe PM, Foon R, Khan KS. Nonsurgical treatment of stress urinary incontinence (SUI): grading of evidence in systematic reviews. BJOG. 2008 Mar; 115(4):435-44.

7. Kadian S, Latthe PM, Afnan M, Toozs-Hobson P. Roasting chestnuts by the fire: a case report of Ramsay’s syndrome. Obstet Gynaecol; 2008 Jan; 28(1):120-1.

8. Latthe PM, Foon R, Toozs-Hobson P. Antibiotic prophylaxis at cystometry: A systematic review and meta-analysis of effectiveness and complications Neurourol Urodyn. 2008; 27(3):167-73.

9. Latthe PM, Kadian S, Parsons M, Toozs-Hobson P. A survey of use of local infiltration in pelvic floor surgery. Gynecological Surgery, 2007 (4): 187-190.

10. Latthe PM, Foon R, Toozs-Hobson P. Transobturator and retropubic tape procedures in stress urinary incontinence: A systematic review and metaanalysis of effectiveness and complications. BJOG 2007; 114(5): 522-531

11. Toozs-Hobson-P, Latthe PM. Critical Evaluation of the Efficacy and Safety of Anticholinergics in Overactive Bladder. European Urology, Supplements, 2007; 6(5): 425-431. Issue title: OAB: What Matters to the Patient?

12. Latthe PM, Proctor ML, Farquhar CM, Johnson N, Khan KS. Surgical interruption of pelvic nerve pathways in dysmenorrhea: a systematic review of effectiveness; Acta Obstet Gynecol Scand. 2007; 86(1):4-15.

13. Farquhar C, Latthe PM. Chronic pelvic pain: aetiology and therapy. Reviews in Gynaecological and Perinatal Practice. 2006 (6): 177-184.

14. Latthe PM, Patodi M, Constantine G. Transobturator tape procedure in stress urinary incontinence: UK experience of a district general hospital. Journal of obstetrics & gynaecology, 2007 (3) 249-252.

15. Latthe PM, Latthe M, Say L, Gulmezoglu M, Khan KS. WHO systematic review of prevalence of chronic pelvic pain: neglected reproductive health morbidity. BMC Public Health, 2006 Jul 6; 6(1):177.

16. Latthe PM, Mignini L, Hills RK, Gray R, Khan KS. Factors predisposing women to chronic pelvic pain: systematic review BMJ 2006 Apr 1;332(7544):749-55

17. Proctor M, Latthe PM, Johnson NP, Farquar C, Khan KS. Surgical interruption of pelvic nerve pathways for primary and secondary dysmenorrhoea; Cochrane Database Syst Rev 2005 Oct 19 ;(4):CD001896.

18. Latthe PM, Braunholtz D, Hills RK, Khan KS, Lilford RJ. Measurement of beliefs about effectiveness of laparoscopic uterosacral nerve ablation BJOG 2005 Feb; 112 (2): 243-6.

19. Mignini LE, Latthe PM, Villar J, Kilby MD, Carroli G, Khan KS Mapping the theories of pre-eclampsia: the role of homocysteine Obstet Gynecol 2005 Feb; 105(2): 411-25

20. Latthe PM, Powell R, Daniels J, Hills RK, Gray R, Gupta JK, Khan KS. Variation in practice of Laparoscopic uterosacral nerve ablation: A European survey. J Obstet Gynaecol August 2004; 24(5): 547-551

21. Zullo-F, Palomba-S, Zupi-E, Russo-T, Morelli-M, Cappiello-F, Mastrantonio-P, Latthe P, Khan-KS. Presacral neurectomy in addition to surgery for endometriosis increased the cure of severe dysmenorrhea. Evidence-based Obstetrics and Gynecology, 2004, 6(1): 15-16

22. Baruah S, Latthe PM, Bhatti N, Ghataura S. Aggressive angiomyxoma of the vulva. Hospital Medicine, April 2004 vol. 65(4): 248-249

23. Latthe PM, Khan KS. Commentary in Evidence Based O &G on the recent trials in neuroablation for pelvic pain; 2003; 11: 6-16

24. Latthe PM, Khan KS. Commentary in Evidence Based O &G on the length of third stage of labour and postpartum haemorrhage 2003; 11: 6-16

25. Baruah S, Latthe PM, Downey G. Presentation of advanced tubal pregnancy J Obstet Gynaecol 2003 Jul; 23(4):435-6.

26. Latthe PM and the LUNA trial collaboration team. The LUNA trial protocol.BMC: http://www.biomedcentral.com/imedia/2080519390195068

27. Kunst H, Groot D, Latthe PM, Latthe M, Khan KS. Accuracy of information on apparently credible websites: survey of five common health topics. BMJ 2002; 324: 581-2

28. Latthe PM, Kilby MD, Jobanputra P, Alner M. Takayasu’s Arteritis, Thrombophilia and pregnancy- case report and review of literature; J Obstet Gynaecol March 2002 vol.22 (2): 228

29. Coomarasamy A, Latthe PM, Papaioannou S, Publicover M, Gee H, Khan KS. Critical appraisal in clinical practice: sometimes irrelevant, occasionally invalid. Journal of Royal Society of Medicine November 2001; 94: 573-77.

30. Latthe PM, Latthe M, Khan KS. Quality of Patient Information on Menorrhagia available on the worldwide web. BJOG 2000; 107(1): 39-43.

31. Latthe M, Latthe PM, Charlton R. Quality of information on emergency contraception on the Internet. Br J Fam Plann January 2000; 26(1): 39-43.

32. Latthe PM, Latthe M, Khan KS. Quality of Information on female sterilisation available on the Internet. J Obstet Gynaecol, 2000; 20 (2): 167-170.

33. Latthe PM, Shafi MI, Rollason TP. Recurrence of Sertoli- Leydig cell tumour in contralateral adolescent ovary –case report and review of literature. Eur J Gynaecol Oncol 2000; vol. XXI (1): 622-63.

34. Latthe PM, Shafi MI. Screening for gynaecological conditions. Current Obstet Gynecol 2000; 11: 31-37.

Books

1. Latthe PM, Khan KS, Gupta JK, Gee H. MRCOG Part II- self-assessment guide, Arnold Publications; 2001.

2. Latthe M, Bath S, Latthe PM. Obstetrics and Gynaecology for primary care, RCGP Publications; November 2003.

Book Chapters

1. Latthe PM, Khan KS. Pelvic pain. Chapter in “Obstetrics and Gynaecology” eds. P. Owen (Arnold, 2nd edition, Edinburgh, 2008)

2. Latthe PM, Toozs-Hobson P. Drugs acting on the lower urinary tract. Chapter in ‘Therapeutic Management of Incontinence and Pelvic Pain: Pelvic Organ Disorders’ eds. J. Laycock and J. Haslam (Springer; 2nd edition, London, 2006)

3. Latthe PM, Keay S. Management of infertility in primary care in Obstetrics and Gynaecology for primary care eds: Latthe M, Bath S, Latthe PM., (RCGP Publications, London, November 2003) Jha S,

Latthe PM. Chronic pelvic pain in Obstetrics and Gynaecology for primary care eds: Latthe M, Bath S, Latthe PM (RCGP Publications, London, November 2003.)

This page was last modified on Wed Apr 11 2012